Sample: Available
Appearance: White powder
Delivery: within 3 days after payment
Certifications: ISO, HACCP, HALAL, KOSHER
Foil bag: 1-10kg; Drum: 20,25kg
- Product Description
High-Purity Matrine: Premium Botanical Alkaloid from Xi'an Linnas Biotech
Xi'an Linnas Biotech Co., Ltd. manufactures pharmaceutical-grade Matrine derived from Sophora genus plants using cutting-edge extraction technology, at 98% purity (HPLC confirmed). Operating under ISO 9001, HACCP, HALAL, and KOSHER certifications, our manufacturing plant guaranties stringent quality control from the selection of raw materials to the inspection of the finished product. We provide batch-to-batch consistency with heavy metals below 10 ppm, residual solvents fulfilling pharmacopeial standards (CP/USP), and microbiological load under 1000 cfu/g thanks to automated manufacturing lines and advanced analytical tools. Linnas is your dependable partner for high-quality alkaloid ingredients because of its quick delivery within three days and extensive OEM/ODM services.
Product Specifications
|
Parameter |
Specification |
|
Assay (HPLC) |
98% min |
|
Appearance |
White powder |
|
Loss on Drying |
≤2.0% |
|
Ash Content |
≤0.1% |
|
Heavy Metals |
≤10 ppm |
|
Lead (Pb) |
≤2 ppm |
|
Arsenic (As) |
≤1 ppm |
|
Total Plate Count |
≤1000 cfu/g |
|
Yeast & Mold |
≤100 cfu/g |
|
Pathogen |
Negative |
|
Residual Solvents |
USP/CP compliant |

Quality Assurance & Testing
Strict adherence to international pharmacopeial standards is necessary for professional Matrine procurement. Several crucial inspection criteria are part of our quality control procedure.
Pure compounds and complete sophocarpidine alkaloid mixes can be distinguished using an HPLC assay. This keeps less expensive alternatives from contaminating the market. Gas Chromatography (GC) examination confirms that extraction solvents stay within safety limits, with benzene totally missing and ethanol below 5000 ppm.
Lead, arsenic, and cadmium levels are regularly below 10 parts per million thanks to heavy metal testing. This reduces the possibility of bioaccumulation in cosmetic and medicinal applications. Testing for ignition residue verifies that the ash content remains below 0.1%, indicating extraordinary levels of purity.
For pharmaceutical-grade applications, microbial load testing keeps the Total Plate Count below 1000 cfu/g. Pathogen screening satisfies strict international safety standards by ensuring the absence of Salmonella and E. coli.
Applications & Benefits
This plant alkaloid has a wide range of practical uses in several industries. It is used by pharmaceutical companies in pain management formulations and anticancer research.
Studies show that it can stop the growth of cancer cells by preventing cell cycles and triggering apoptosis. Research on lung cancer A549 cells reveals that it causes targeted cell death processes by upregulating microRNA-126 expression and downregulating VEGF.
Its interaction with mu-opioid (MOR) and kappa-opioid (KOR) receptors is utilized in pain management applications. Cholinergic and dopaminergic neurotransmission modulation significantly reduces pain in chronic constriction injury models, according to clinical investigations.
Its capacity to raise TH2 cytokines while lowering IgE production is advantageous for allergy therapy formulations. It successfully reduces allergy-induced airway inflammation in asthma patients by downregulating SOCS3 expression.

Manufacturing Capabilities
Automated extraction lines and climate-controlled processing areas are hallmarks of our production plant. Modern HPLC systems keep an eye on purity at every stage of manufacture, guaranteeing a constant 98% Matrine content.
Systems for recovering solvents reduce their negative effects on the environment while keeping costs down. Our extraction method maximizes production without sacrificing purity by using food-grade ethanol under carefully regulated temperature and pressure conditions.
Every batch is accompanied by quality documentation, such as third-party testing results, MSDS, and Certificates of Analysis (COA). Complete traceability guaranties regulatory compliance in global markets from the procurement of raw materials to the final packaging.
Packaging & Storage
Different order amounts are accommodated by standard packing options:
- Foil bags: 1–10 kg (ideal for small-batch production and sampling)
- 20–25 kg fiber drums are appropriate for commercial manufacturing.
Keep out of direct sunlight and store in cool, dry conditions. When stored properly, sealed containers remain stable for 24 months. Private label brands can choose from custom packaging options.
Stacking & Formulation Synergy
For increased efficacy, formulators often mix this alkaloid with complementing substances. When combined with palmitoylethanolamide (PEA), potent nerve pain treatment formulations that target several pain pathways at once are produced.
Combining high-potency saffron extract with mood-enhancing compounds is beneficial. For all-encompassing mood support, this combination activates the PI3K/Akt/mTOR pathway in addition to serotonin-mediated benefits.
High-EPA fish oil is added to cardiovascular compositions to enhance their anti-inflammatory qualities. This combination improves cognitive function and offers comprehensive support for heart health.

Frequently Asked Questions
Q: What is the purity level of your product?
A: Our pharmaceutical-grade powder satisfies stringent CP/USP pharmacopeial standards and maintains a minimum purity of 98%, as confirmed by HPLC testing.
Q: How fast are you able to deliver orders?
A: After payment is confirmed, standard items are shipped within three days. For urgent needs, expedited shipping alternatives are available.
Q:Do you offer samples for examination?
A: Before submitting large orders, samples are provided for quality assessment. To discuss your particular testing needs, get in touch with us.
Q: Which certifications does your establishment possess?
A: In order to ensure compliance with worldwide regulatory standards, our manufacturing plant possesses ISO 9001, HACCP, HALAL, and KOSHER certifications.
Q: Is it possible to modify requirements for particular uses?
A: Absolutely. Our technical staff collaborates closely with clients to create specifications, formulas, and packaging solutions that precisely meet your needs.
Q: What is the order quantity minimum?
A: MOQ varies according on customization requirements and package format. For comprehensive information on your particular project, get in touch with our sales team.
Contact Us for Premium Matrine Supply
Ready to use the Matrine to source pharmaceutical-grade botanical alkaloids from a certified manufacturer?Email us at cathy@linnas.com.cn for quotations, samples, or technical support.









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