Cryptotanshinone

Cryptotanshinone - Premium Botanical Extract for Pharmaceutical & Cosmetic Applications

Xi'an Linnas Biotech Co., Ltd. manufactures high-purity Cryptotanshinone produced from the dried roots of Salvia miltiorrhiza Bunge (Danshen) and standardized to 20% by HPLC. This lipophilic diterpenoid quinone has a special double bond structure in its dihydrofuran ring, which gives it strong ability to block Stat3.Our facility follows ISO 9001, HACCP, HALAL, and KOSHER standards, ensuring that each batch is consistent and meets microbiological quality standards. Samples are available, and shipping is finished three days after payment is confirmed.

Technical Specifications

Why Choose Linnas Cryptotanshinone?

Supplier knowledge and the reliability of ingredients are very important for your recipe's success.Our manufacturing process uses modern testing tools along with automated production lines to keep the quality the same during every batch.

Every order comes with detailed test results, called a COA. These results include special fingerprint-like data from chromatography that helps tell Cryptotanshinone apart from similar compounds like Tanshinone IIA and Dihydrotanshinone I.We also use a test called ICP-MS to make sure heavy metals are at safe levels, and we follow ICH Q3C guidelines for checking any leftover solvents.

Our team of experts can help you create your product through formulation advice. We offer both OEM and ODM services tailored to your specific market needs, whether you're making supplements for metabolic health or skincare products for acne.This full approach helps speed up the time it takes to bring new products to market and makes your supply chain easier to manage.

Pharmaceutical & Cosmetic Applications

This substance effectively combats Propionibacterium acnes without causing resistance. Your cosmetic R&D teams can use its dual anti-inflammatory and sebum-regulating properties for INCI-listed therapies for oily and acne-prone skin.

Metabolic Health Products: Formulation scientists add this ingredient to PCOS management supplements because it reduces androgen synthesis and stimulates AMPK pathways. An essential gap in the treatment of metabolic syndrome is filled by this non-hormonal strategy.

Research-grade reagents: Biomedical labs employ high-purity isolates as inhibitors to prevent STAT3 from forming dimers in cancer research. The chemical is useful for researching how the tumor environment is regulated since it is lipophilic, which allows it to cross cell membranes.

Quality Assurance Protocol

The main test technique used in our QC lab is HPLC analysis, which verifies the diterpenoid content while checking for oxidation contaminants. By measuring the leftover solvents, gas chromatography with headspace analysis (GC-HS) makes sure that the levels of ethanol and methanol are within international standards.

Microbiological tests show that there are no S.aureus or E.coli present, and the total number of aerobic bacteria is less than 1000 CFU/g.To prevent the product from breaking down due to light exposure during storage and transport, each production batch is packed in vacuum-sealed containers that block out light.

All the necessary paperwork is sent to your procurement team to support your applications to the FDA, EMA, or other health authorities. The material safety data sheet (MSDS), a certificate of analysis (COA) containing cytotoxicity test findings, and data demonstrating the product's stability over time are all included in this.

Formulation Considerations

Your primary technical difficulty is low water solubility, which affects how well the drug is absorbed by the body.Professionals employ strategies including cyclodextrin inclusion complexes, solid dispersion techniques, and nano-emulsification to improve absorption through the skin or digestive system.

The material is stable when it is solid and kept out of the light and moisture. But while it is in liquid form, it needs to be protected from degradation, which is accomplished by adding UV-blockers and antioxidants.

To validate shelf-life characteristics, your R&D methods should include accelerated stability testing in accordance with ICH principles. To maximize cutaneous distribution for topical treatments, mix with penetration enhancers. Because lipid-based delivery techniques improve the way oral supplements function in the body, they are preferable to powder encapsulation.

Frequently Asked Questions

Q: What distinguishes this compound from Tanshinone IIA?

A: This chemical has higher antibacterial characteristics and a unique ability to impact androgen receptors due to a structural difference, notably a double bond in the furan ring.Tanshinone IIA is primarily utilized for heart health and antioxidant applications.

Q: Which manufacturing process enhances the product's absorption by the body?

A: Because it dissolves poorly in water, specific techniques are required to improve the body's absorption of it. Utilizing cyclodextrin complexation, solid dispersion, or nano-emulsification enhances absorption on the skin and in the stomach.

Q: Is it possible to utilize this material in cosmetics?

A: INCI designations refer to it as Salvia Miltiorrhiza Root Extract (enriched). Because of its antibacterial and anti-inflammatory properties, it works well in solutions for oily and acne-prone skin.

Q: What storage circumstances contribute to the product's stability?

A: Keep it between 2 and 8°C in vacuum-sealed, light-blocking containers. Solid forms are stable at ambient temperature, whereas liquid forms rapidly degrade when exposed to UV radiation.

Q: What safety records do you offer?

A: MSDS, COA with cytotoxicity tests, heavy metal analysis, and microbiology reports that adhere to USP and EP requirements are included with every order.

Partner With Linnas for Reliable Supply

Contact our technical sales team at cathy@linnas.com.cn to request samples, discuss formulation requirements. Experience the difference that pharmaceutical-grade manufacturing standards bring to your Cryptotanshinone development.